Cell-Mate3D™ is an injectable, tissue-like matrix that offers researchers a biologically relevant microenvironment for in vitro and in vivo biomedical research. It is chemically defined: composed of naturally occurring biopolymers Hyaluronic Acid (HA) and Chitosan (CT).
- HA is a linear polysaccharide found in the extracellular matrix of connective, epithelial, and neural tissues. It is involved in cell proliferation, migration, embryonic development, and wound healing. HA also plays a role in cancer biology.
- CT, derived from Chitin, is a positively charged polysaccharide that is found in the exoskeleton of crustaceans.
When Cell-Mate3D™ dry blend is combined with cells in hydration fluid, Cell-Mate3D™ matrix forms instantly through electrostatic interactions between HACOO– groups and CTNH3+ groups. This interaction results in Poly-Electrolytic-Complex fibers that give structure to the construct.