Cell-Mate3D™ matrix provides your cells with an ideal microenvironment for disease modeling and regenerative medicine research. It is ideal for Cancer cells to model the tumor microenvironment and for stem cells to differentiate toward Central Nervous System tissue.

Advance your research with Cell-Mate3D™

• Tissue-like stiffness better mimics in vivo extracellular environment
• Can allow for emergence of complex microtissues/organoids
• Chemically Defined and Injectable
• Replace up to 20%* of hydration fluid with other components
• ECM components for further customization

*May affect matrix stiffness

Advantages over other 3D culture options

• Permits long-term 3D cultures without producing a necrotic core (depending on cell type)
• No chemical or UV crosslinking
• Use both in vitro and in vivo (injectable)
• Biocompatible
• Cells distributed throughout the matrix
• Cell-Mate3D is a translational product as individual components have Drug Master Files with the FDA.

Cell types that have been cultured in Cell-Mate3D

Primary Cancer Cells

• Fibrosarcoma (HT1080)
• Melanoma (C8161)
• Glioblastoma (GBM-22)
• B-Lymphoma
• Rare Brain Tumor
• Colon Cancer
• Breast Cancer
• Pancreatic Cancer
• Ovarian cancer

Stem Cells

• Human iPSCs
• Human MSCs
• Mouse ES
• Mouse MSC
• Canine MSC
• Exocrine primary progenitor cells
• 3T3 Mouse Fibroblasts
• Alveolar cells (pneumocytes type I/II)
• Retinal rods (human primary)

Cancer Cell Lines

• Breast cancer (MCF7)
• HeLa
• Kidney (HEK293)
• Pancreatic Cancer (MiaPaca-2)
• Lung adenocarcinoma (A549)
• Lung adenocarcinoma (HCC358)
• Bladder (T24)
• AU565