03 Apr Creating a Tumor Microenvironment with a Hypoxic Gradient using Cell-Mate3D
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Cancerous tumors are heterogeneous tissues with a dynamic microenvironment. They exhibit an oxygen gradient with outer regions of well-oxygenated (normoxic) tissue alongside poorly-oxygenated regions experiencing hypoxia (1). Hypoxia is essential for tumor development and many studies have shown that tumor cells in hypoxic regions distant from...