News Archives – BRTI Life Sciences

01 May Visualizing Apoptosis in 3D Cell Cultures

Posted at 03:13h in News by Beth Lindborg

Apoptosis, or programmed cell death, is an important cellular mechanism that is critical in development and tissue homeostasis. Apoptosis also plays a role in cancer biology. For example, visualizing apoptosis in response to treatments is one way to characterize potential therapies. While 3D cell cultures are ideal...

03 Apr Creating a Tumor Microenvironment with a Hypoxic Gradient using Cell-Mate3D

Posted at 18:19h in News by Beth Lindborg

Cancerous tumors are heterogeneous tissues with a dynamic microenvironment. They exhibit an oxygen gradient with outer regions of well-oxygenated (normoxic) tissue alongside poorly-oxygenated regions experiencing hypoxia (1). Hypoxia is essential for tumor development and many studies have shown that tumor cells in hypoxic regions distant from...

05 Oct New Article! 3D Cell Culture in a Self-Assembled Nanofiber Environment.

Posted at 08:59h in News by anySiteAdmin

[vc_row][vc_column width="1/1"][vc_column_text]Researchers at BRTI Life Sciences recently published an article in PLOS ONE entitled: 3D Cell Culture in a Self-Assembled Nanofiber Environment. The article demonstrates how Cell-Mate3D can be used to analyze complex 3D cultures. Read the press release.[/vc_column_text][/vc_column][/vc_row]...

01 Jun Cell-Mate3D is mentioned in a recent Nature Methods review article

Posted at 14:47h in News by anySiteAdmin

Cell-Mate3D is mentioned in a recent Nature Methods review article by Steven Caliari and Jason Burdick, "A Practical Guide to Hydrogels for Cell Culture”....

01 Jun Cell-Mate3D Induces Rapid Generation of Cerebral Organoids

Posted at 14:44h in News by anySiteAdmin

Read the article in Stem Cell Translational Medicine: Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium....

22 May Application of Cell-Mate 3D matrix

Posted at 17:27h in News by anySiteAdmin

Application of Cell-MateTM 3D matrix in modeling artificial breast ductal cancer as well as control “normal” tissues...

19 May Tissue Engineering and Regenerative Medicine

Posted at 12:34h in News by anySiteAdmin

Abstract: Tissue organoids are a promising technology that may accelerate development of the societal and NIH mandate for precision medicine. Here we describe a robust and simple method for generating cerebral organoids (cOrgs) from human pluripotent stem cells by using a chemically defined hydrogel material...

09 Jul BRTI Life Sciences to provide “tissue-like” microenvironment to support pancreatic islets for JDRF funded University of Minnesota study.

Posted at 15:16h in News by anySiteAdmin

BRTI Life Sciences' unique 3D matrix will be included in a study at the University of Minnesota of immunoisolated islets in a structured biomimetic environment to treat insulin-dependent diabetes. The study, which is fully funded by the Juvenile Diabetes Research Foundation (JDRF), employs a device, including islets...

12 May Cell-Mate3D™ Featured at Regenerative Medicine Conference at Hilton Head

Posted at 14:42h in News by anySiteAdmin

Podium Presentation: Induction of Cerebral Organoids from Human Induced Pluripotent Stem Cells using a Chemically Defined Hydrogel and Defined Culture Medium. Timothy D. O'Brien https://www.regenerativemedicineworkshop.com/users/timothy-d-obrien Poster Presentation: Culture and Trilineage Differentiation of hMSCs Within a Novel 3D Microenvironment. Applications for in vitro and in vivo Biomedical Research. Beth A. Lindborg, Yi Wen Chai, Connor B....

06 May New publication using Cell-Mate3D

Posted at 18:39h in News by anySiteAdmin

"A chitosan-hyaluronan based hydrogel-hydrocolloid supports in vitro culture and differentiation of human mesenchymal stem/stromal cells (MSCs)" was recently accepted in Tissue Engineering Part A. This article describes how Cell-Mate3D can improve differentiation potential and induce more complex structures compared to 2D cultures. Click here for the abstract....