News – BRTI Life Sciences

05 May Cerebral Organoids Generated using Cell-Mate3D Mentioned in Mini-Me Article

Posted at 22:10h in Articles by Beth Lindborg

Two new articles published in Nature are the focus of a new Scientific American article: "Mini-Me Brains Mimic Disease, Raise Hope for Eventual Therapies". One article, "Assembly of Functionally Integrated Human Forebrain Spheroids" focuses on the creation of a new disease model where brain organoids were generated from...

01 May Visualizing Apoptosis in 3D Cell Cultures

Posted at 03:13h in News by Beth Lindborg

Apoptosis, or programmed cell death, is an important cellular mechanism that is critical in development and tissue homeostasis. Apoptosis also plays a role in cancer biology. For example, visualizing apoptosis in response to treatments is one way to characterize potential therapies. While 3D cell cultures are ideal...

03 Apr Creating a Tumor Microenvironment with a Hypoxic Gradient using Cell-Mate3D

Posted at 18:19h in News by Beth Lindborg

Cancerous tumors are heterogeneous tissues with a dynamic microenvironment. They exhibit an oxygen gradient with outer regions of well-oxygenated (normoxic) tissue alongside poorly-oxygenated regions experiencing hypoxia (1). Hypoxia is essential for tumor development and many studies have shown that tumor cells in hypoxic regions distant from...

28 Feb The Cancer Stem Cell Hypothesis and How It Could Impact Cancer Treatment

Posted at 20:46h in Articles by anySiteAdmin

Stem cell research has been a topic of interest for a number of years. Even if you have only a vague understanding of what stem cells are, you likely know that they hold great promise for treating any number of conditions or diseases. But there's also...

20 Feb The Evolution of Tumor Models: Why Cancer Researchers Shifted Their Focus To 3D

Posted at 20:59h in Articles by anySiteAdmin

For many years, two-dimensional cell cultures were one of the only options researchers had to create and study cell growth and interaction. But 2D systems have definitive limitations: unlike how they behave in the human body, cells can't grow in all directions in 2D, which...

05 Oct New Article! 3D Cell Culture in a Self-Assembled Nanofiber Environment.

Posted at 08:59h in News by anySiteAdmin

[vc_row][vc_column width="1/1"][vc_column_text]Researchers at BRTI Life Sciences recently published an article in PLOS ONE entitled: 3D Cell Culture in a Self-Assembled Nanofiber Environment. The article demonstrates how Cell-Mate3D can be used to analyze complex 3D cultures. Read the press release.[/vc_column_text][/vc_column][/vc_row]...

01 Jun Cell-Mate3D is mentioned in a recent Nature Methods review article

Posted at 14:47h in News by anySiteAdmin

Cell-Mate3D is mentioned in a recent Nature Methods review article by Steven Caliari and Jason Burdick, "A Practical Guide to Hydrogels for Cell Culture”....

01 Jun Cell-Mate3D Induces Rapid Generation of Cerebral Organoids

Posted at 14:44h in News by anySiteAdmin

Read the article in Stem Cell Translational Medicine: Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium....

22 May Application of Cell-Mate 3D matrix

Posted at 17:27h in News by anySiteAdmin

Application of Cell-MateTM 3D matrix in modeling artificial breast ductal cancer as well as control “normal” tissues...

19 May Tissue Engineering and Regenerative Medicine

Posted at 12:34h in News by anySiteAdmin

Abstract: Tissue organoids are a promising technology that may accelerate development of the societal and NIH mandate for precision medicine. Here we describe a robust and simple method for generating cerebral organoids (cOrgs) from human pluripotent stem cells by using a chemically defined hydrogel material...